Deep Fungal Infections

Sorry, this is not the correct diagnosis.

The oral cavity is a site where a number of deep fungal infections can occur. However, deep fungal infections are not commonly found in the U.S. These diseases tend to occur in developing countries in areas such as Latin America and Africa. This type of tissue necrosis and swelling can be associated with an infection such as blastomycosis, which can occur in the United States and Canada and tends to occur mostly in otherwise healthy adult males with a male-to-female ratio of 9:1. Histoplasmosis, on the other hand, is a disease that is seen in elderly and debilitated patients, especially those who are chronically ill and immunecompromised (8). It occurs in the Ohio-Mississippi River area and it can affect the general population, usually as a subclinical disease. It is unusual to develop histoplasmosis of the mouth without lung involvement. Other deep fungal infection such as zygomycosis (mucormycosis) can also occur in the oral cavity, especially in the maxillary sinuses and nose, breaking through the palate. These lesions occur in uncontrolled diabetics and immunecompromised patients. Although the clinical presentation of fast growth and soft tissue necrosis is compatible with a deep fungal infection, the histology in this case was not supportive of such disease.